Thyroid Disease: Types, Symptoms, Causes, Preventions, Risk Factors, Complications & Treatment
Thyroid Disease
[A Complete Guide]
Thyroid disorder is a common problem that affects more women than men. The thyroid is a butterfly-shaped gland located inside the neck and just above the collarbone. The thyroid is a type of endocrine gland that makes hormones. There are mainly two types of thyroid- hypothyroid and hypothyroid. In hyperthyroidism the thyroid is produced in excess whereas in hypothyroidism the production of this hormone is reduced.
What is Thyroid?
The thyroid has an endocrine gland that produces two hormones called triiodothyronine (T3) and thyroxine (T4). The production and secretion of these hormones are controlled by thyroid-stimulating hormones (TSH). TSH is produced in the pituitary whose secretion is controlled by thyroid releasing hormone or TRH. These hormones are responsible for the normal metabolic process of the body.
Thyroid problems arise when the thyroid gland produces more or less hormones. An imbalance in the production of hormones can occur due to the formation of cancerous or cancerous cells in the autoimmune or thyroid gland or inflammation in the gland. Globally, more women suffer from this disease than men. 0.5% of women suffer from thyroid as compared to 0.5% of men. The formation of more or less thyroid hormone affects every cell in the body.
Types of Thyroid Disease
Thyroid related problems:
- Hyperthyroidism: In this, due to over-activation of the thyroid gland, excessive secretion of thyroid hormone starts.
- Hypothyroidism: In this, the thyroid gland releases less than normal thyroid hormone.
- Thyroid Cancer: The most dangerous form of endocrine tumor is thyroid cancer. Depending on the tissues, thyroid cancer can be classified as follows-
- Differential Thyroid Cancer: Differential thyroid cancer occurs when papillary thyroid cancer and follicular thyroid cancer occur together. This type of cancer comes from epithelial cells and is the most common form of thyroid cancer.
- Anaplastic Thyroid Cancer: Anaplastic thyroid cancer is a rare and rapidly growing cancer that is very difficult to treat. Only two percent of cancer is anaplastic thyroid cancer. This cancer usually occurs in adults 60 or older.
Symptoms of Thyroid Disease
- Goitre disease
- Lose weight
- Nervousness, anxiety, discomfort or mood swings
- Tiredness
- Feeling too hot
- Breathlessness
- Heartbeat fast
- Sleep less
- Excessive thirst
- Redness or dryness in eyes
- hair fall
- Gaining weight
- Weakening of nails and hair
- Skin dryness and thinning
- Hair loss
- Feeling too cold
- Depression
- Muscle stiffness
- Sore throat
- Mental stress
- Rapid lump in the throat
- Neck swelling
- Change in voice
- Difficulty swallowing food
- respiratory distress
- A persistent cough without any infection or allergy
Causes of Thyroid Disease
1.There are various causes of Hyperthyroidism:
- Graves disease: It is an autoimmune disease in which auto antibodies stimulate the gland to produce and release a large amount of thyroid hormone. This problem is seen in more women than men.
- Knee in thyroid gland: Due to formation of knot (which is not cancerous) on thyroid gland, excessive amount of hormones can be released.
- Excess intake of iodine: Iodine is an essential micronutrient for the production of thyroid hormone. However, excessive intake of iodine can lead to hyperthyroidism.
- Pregnancy: Hyperthyroidism can occur due to hormonal changes during pregnancy. The production of thyroid hormones may increase when cancerous cells develop in the pituitary gland.
Risk factor:
- Pregnancy
- Smoking
- Autoimmune diseases such as Sjogren's syndrome
There are various causes of Hypothyroidism:
Causes of primary Hypothyroidism:
- Hashimoto's disease: The thyroid gland becomes less active due to autoimmune inflammation in the thyroid gland.
- Deficiency of Iodine: Iodine plays an important role in the production of thyroid hormone after the thyroid gland and can cause hyperthyroidism.
- Thyroidectomy: A surgical procedure in which the entire thyroid gland or some part of the thyroid gland is removed. This may later take the form of hypothyroidism.
- Radiotherapy
- Thyroid dysgenesis
- Congenital hyperthyroidism
Causes of secondary Hypothyroidism:
- Pituitary adenoma (growth of cancerous cells)
- Pituitary surgery
- Head trauma
- Hypothalamic tumor
Risk factor:
- If a member of the family has hypothyroidism, the risk of it increases in other members also. Congenital hypothyroidism is common in this condition. Apart from this, a diet with low iodine is also an important factor in hypothyroidism.
There are various causes of Thyroid Cancer:
- Genetic cause: The person with thyroid cancer has the highest risk of cancer from the genes.
- Radiation: Carcinogen is a popular radiation. These radiation cause carcinogenic changes.
- Diabetes: Increased insulin resistance and TSH levels can increase the risk of thyroid cancer in diabetes patients.
- Hormone: Estrogen plays an important role in thyroid cancer. The study has revealed that women who underwent hysterectomy (uterine removal surgery) had a higher risk of thyroid cancer.
- Lifestyle: Taking high amounts of nitrates in the diet and food additives can also cause thyroid cancer. Smoking and lack of physical activity can also play an important role in causing thyroid cancer.
- Autoimmunity: Patients with Graves disease and Hashimoto thyroiditis have a higher risk of thyroid cancer.
Risk factor:
- Women are at higher risk of this
- Genetic
- TSH label increase
- Autoimmune disease
- Exposure to toxic chemicals and radiation
Prevention of Thyroid Disease
Hyperthyroidism
Hypothyroidism
Thyroid Cancer
Treatment of Thyroid Disease
Hyperthyroidism
- Medications: Radioactive iodine ablation, anti-thyroid drugs such as neomercazole (to slow the release of hormones) and anti-inflammatory medications (to relieve symptoms) are advised.
- Surgical removal of the affected part of the thyroid gland or thyroidectomy.
- Use of artificial tears to relieve dryness of eyes.
Lifestyle Changes:
Hypothyroidism
Lifestyle Changes:
Thyroid Cancer
- Surgery: The whole or part of the thyroid gland and the lymph nodes of the neck are removed by surgery.
- The remaining thyroid tissue after surgery is removed with radioactive iodine therapy.
- Radiation therapy
- Chemotherapy: Intravenous anti-cancer drugs.
- Targeted therapy: eliminating cancerous tissues with drugs.
Lifestyle changes:
Risk and Complications of Thyroid Disease
Hyperthyroidism
- Cardiovascular diseases such as stroke and hot failure
- Paralysis
- Osteoporosis
- Infertility due to irregular menstruation
- Thyroid storm in the part where thyroid hormone is released in some quantity
Hypothyroidism
- Atherosclerosis (deposition of cholesterol inside the arteries) can cause problems when the thyroid gland is less active. In some cases, it can also cause the thyroid gland to enlarge to meet hormonal requirements.
- Apart from this, a condition of myxedema coma can also occur due to hypothyroidism. Myxedema coma is a very dangerous condition. It is characterized by very low production of thyroid hormone.
Thyroid Cancer
- The cancer can spread to nearby areas and affect the function of the vocal tract. It can also spread to the lymph nodes due to which it can become more difficult.